Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. Examination of RIBE in irradiated A549 cells.
  • Fig. S2. Therapeutic effect of RT-MPs.
  • Fig. S3. RT-MPs induce ferroptosis in tumor cells.
  • Fig. S4. RT-MPs promote immunogenic cell death.
  • Fig. S5. Macrophages show robust phagocytosis of RT-MPs.
  • Fig. S6. Therapeutic effect of combination treatment with RT-MPs and anti–PD-1 depends on immune system activation.
  • Fig. S7. Therapeutic effect of RT-MPs on A549-DDR cells.
  • Fig. S8. Hemanalysis and biochemical analyses.
  • Table S1. Sequences of primers for RT-qPCR analysis.
  • Table S2. Antibodies used in this article.

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.avi format). Radiated LLC-RFP released more microparticles.
  • Movie S2 (.avi format). Unradiated LLC-RFP released less microparticles.
  • Movie S3 (.avi format). Macrophages and LLC-RFP cells.
  • Movie S4 (.avi format). Macrophages and RT-MP–treated LLC-RFP cells.
  • Movie S5 (.avi format). Two hours after RT-MPs’ injection.
  • Movie S6 (.avi format). Twenty-four hours after RT-MPs’ injection.
  • Movie S7 (.avi format). Macrophages phagocytose PKH26-labeled RT-MPs in vitro.
  • Movie S8 (.avi format). RT-MP–treated macrophages and LLC-RFP cells.

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