Science Advances

Supplementary Materials

The PDF file includes:

  • Legends for movies S1 to S4
  • Fig. S1. Images of tumor aggregate growth in alginate capsule.
  • Fig. S2. Pressure and oxygen mass fraction tumor cell growth dependence.
  • Fig. S3. Numerical diffusive flow in alginate capsule.
  • Fig. S4. Influence of hypoxia on volume evolution for spherical and tubular capsule.
  • Fig. S5. Numerical radial plots of tubular capsule primary variables.
  • Fig. S6. Tube radius as a function of distance from the cylindroid center along the main axis.

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mp4 format). Phase-contrast time-lapse video of a growing multicellular spheroid in a spherical capsule.
  • Movie S2 (.mp4 format). Phase-contrast time-lapse video of growing multicellular cylindroids in a cylindrical capsule.
  • Movie S3 (.avi format). Numerical simulations of aggregate growth in spherical capsule.
  • Movie S4 (.avi format). Numerical simulations of aggregate growth in tubular capsule.

Files in this Data Supplement: