PT - JOURNAL ARTICLE AU - Balfourier, François AU - Bouchet, Sophie AU - Robert, Sandra AU - De Oliveira, Romain AU - Rimbert, Hélène AU - Kitt, Jonathan AU - Choulet, Frédéric AU - , AU - , AU - Paux, Etienne TI - Worldwide phylogeography and history of wheat genetic diversity AID - 10.1126/sciadv.aav0536 DP - 2019 May 01 TA - Science Advances PG - eaav0536 VI - 5 IP - 5 4099 - http://advances.sciencemag.org/content/5/5/eaav0536.short 4100 - http://advances.sciencemag.org/content/5/5/eaav0536.full SO - Sci Adv2019 May 01; 5 AB - Since its domestication in the Fertile Crescent ~8000 to 10,000 years ago, wheat has undergone a complex history of spread, adaptation, and selection. To get better insights into the wheat phylogeography and genetic diversity, we describe allele distribution through time using a set of 4506 landraces and cultivars originating from 105 different countries genotyped with a high-density single-nucleotide polymorphism array. Although the genetic structure of landraces is collinear to ancient human migration roads, we observe a reshuffling through time, related to breeding programs, with the appearance of new alleles enriched with structural variations that may be the signature of introgressions from wild relatives after 1960.