Table 1 DAVID functional annotation clustering analysis on 2077 of the 3367 DEGs in honey bee larvae consuming p-coumaric acid.

Annotation cluster	Term	Count	P	Benjamini
Cluster 1 (enrichment score: 11.08)	Imaginal disc development	131	8.90 × 10⁻¹⁶	2.40 × 10⁻¹²
	Post-embryonic organ development	100	7.10 × 10⁻¹⁴	9.40 × 10⁻¹¹
	Imaginal disc morphogenesis	96	1.80 × 10⁻¹³	1.60 × 10⁻¹⁰
	Post-embryonic organ morphogenesis	96	1.80 × 10⁻¹³	1.60 × 10⁻¹⁰
	Post-embryonic morphogenesis	109	2.70 × 10⁻¹²	1.80 × 10⁻⁹
	Metamorphosis	111	2.80 × 10⁻¹²	1.50 × 10⁻⁹
	Wing disc development	92	4.90 × 10⁻¹²	2.20 × 10⁻⁹
	Instar larval or pupal morphogenesis	107	4.90 × 10⁻¹²	1.90 × 10⁻⁹
	Post-embryonic development	126	5.30 × 10⁻¹²	1.80 × 10⁻⁹
	Instar larval or pupal development	120	4.10 × 10⁻¹¹	1.10 × 10⁻⁸
	Imaginal disc–derived appendage morphogenesis	79	1.10 × 10⁻¹⁰	2.80 × 10⁻⁸
	Wing disc morphogenesis	74	2.00 × 10⁻¹⁰	4.30 × 10⁻⁸
	Post-embryonic appendage morphogenesis	76	2.20 × 10⁻¹⁰	4.50 × 10⁻⁸
	Appendage morphogenesis	79	2.20 × 10⁻¹⁰	4.20 × 10⁻⁸
	Imaginal disc–derived appendage development	79	2.80 × 10⁻¹⁰	4.90 × 10⁻⁸
	Imaginal disc–derived wing development	73	3.30 × 10⁻¹⁰	5.50 × 10⁻⁸
	Appendage development	79	5.40 × 10⁻¹⁰	8.40 × 10⁻⁸
Cluster 2 (enrichment score: 9.73)	Transcription	131	7.10 × 10⁻¹²	2.10 × 10⁻⁹
	Regulation of transcription	192	1.10 × 10⁻⁹	1.60 × 10⁻⁷
	Regulation of transcription, DNA-dependent	139	9.40 × 10⁻⁶	5.80 × 10⁻⁴
	Regulation of RNA metabolic process	147	6.60 × 10⁻⁵	3.10 × 10⁻³
Cluster 3 (enrichment score: 6.98)	ncRNA metabolic process	49	1.30 × 10⁻⁸	1.80 × 10⁻⁶
	ncRNA process	38	2.30 × 10⁻⁸	3.00 × 10⁻⁶
	tRNA metabolic process	36	5.10 × 10⁻⁷	4.70 × 10⁻⁵
	tRNA process	23	7.60 × 10⁻⁷	6.30 × 10⁻⁵