FSFs in boldface could be potential VSFs based on the criterion described in the text. FSFs were referenced by either SCOP ID or css. For example, the P-loop containing NTP hydrolase FSF is c.37.1, where “c” is the α/β class of secondary structure present in the protein domain, “37” is the fold, and “1” is the FSF.
| SCOP ID | SCOP css | Venn group | FSF description | Distribution |
| 69070 | a.150.1 | V | Anti-sigma factor AsiA | dsDNA |
| 55064 | d.58.27 | V | Translational regulator protein regA | dsDNA |
| 48493 | a.120.1 | V | Gene 59 helicase assembly protein | dsDNA |
| 89433 | b.127.1 | V | Baseplate structural protein gp8 | dsDNA |
| 69652 | d.199.1 | V | DNA binding C-terminal domain of the transcription factor MotA | dsDNA |
| 56558 | d.182.1 | V | Baseplate structural protein gp11 | dsDNA |
| 49894 | b.28.1 | V | Baculovirus p35 protein | dsDNA |
| 160957 | e.69.1 | V | Poly(A) polymerase catalytic subunit–like | dsDNA |
| 51289 | b.85.5 | V | Tlp20, baculovirus telokin-like protein | dsDNA |
| 88648 | b.121.6 | V | Group I dsDNA viruses | dsDNA |
| 161240 | g.92.1 | V | T-antigen–specific domain–like | dsDNA |
| 118208 | e.58.1 | V | Viral ssDNA binding protein | dsDNA |
| 54957 | d.58.8 | V | Viral DNA binding domain | dsDNA |
| 51332 | b.91.1 | V | E2 regulatory, transactivation domain | dsDNA |
| 56548 | d.180.1 | V | Conserved core of transcriptional regulatory protein vp16 | dsDNA |
| 90246 | h.1.24 | V | Head morphogenesis protein gp7 | dsDNA |
| 47724 | a.54.1 | V | Domain of early E2A DNA binding protein, ADDBP | dsDNA |
| 57917 | g.51.1 | V | Zn binding domains of ADDBP | dsDNA |
| 49889 | b.27.1 | V | Soluble secreted chemokine inhibitor, VCCI | dsDNA |
| 89428 | b.126.1 | V | Adsorption protein p2 | dsDNA |
| 82046 | b.116.1 | V | Viral chemokine binding protein m3 | dsDNA |
| 158974 | b.170.1 | V | WSSV envelope protein-like | dsDNA |
| 47852 | a.62.1 | V | Hepatitis B viral capsid (hbcag) | dsDNA-RT |
| 111379 | f.47.1 | V | VP4 membrane interaction domain | dsRNA |
| 48345 | a.115.1 | V | A virus capsid protein alpha-helical domain | dsRNA |
| 69908 | e.35.1 | V | Membrane penetration protein mu1 | dsRNA |
| 75347 | d.13.2 | V | Rotavirus NSP2 fragment, C-terminal domain | dsRNA |
| 69903 | e.34.1 | V | NSP3 homodimer | dsRNA |
| 75574 | d.216.1 | V | Rotavirus NSP2 fragment, N-terminal domain | dsRNA |
| 58030 | h.1.13 | V | Rotavirus nonstructural proteins | dsRNA |
| 49818 | b.19.1 | V | Viral protein domain | dsRNA, minus-ssRNA, plus-ssRNA |
| 88650 | b.121.7 | V | Satellite viruses | ssDNA |
| 48045 | a.84.1 | V | Scaffolding protein gpD of bacteriophage procapsid | ssDNA |
| 50176 | b.37.1 | V | N-terminal domains of the minor coat protein g3p | ssDNA |
| 75404 | d.213.1 | V | VSV matrix protein | Minus-ssRNA |
| 118173 | d.293.1 | V | Phosphoprotein M1, C-terminal domain | Minus-ssRNA |
| 69922 | f.12.1 | V | Head and neck region of the ectodomain of NDV fusion glycoprotein | Minus-ssRNA |
| 101089 | a.8.5 | V | Phosphoprotein XD domain | Minus-ssRNA |
| 58034 | h.1.14 | V | Multimerization domain of the phosphoprotein from Sendai virus | Minus-ssRNA |
| 50012 | b.31.1 | V | EV matrix protein | Minus-ssRNA |
| 48145 | a.95.1 | V | Influenza virus matrix protein M1 | Minus-ssRNA |
| 143021 | d.299.1 | V | Ns1 effector domain–like | Minus-ssRNA |
| 161003 | e.75.1 | V | Flu NP-like | Minus-ssRNA |
| 160453 | d.361.1 | V | PB2 C-terminal domain–like | Minus-ssRNA |
| 101156 | a.30.3 | V | Nonstructural protein ns2, Nep, M1 binding domain | Minus-ssRNA |
| 160892 | d.378.1 | V | Phosphoprotein oligomerization domain–like | Minus-ssRNA |
| 56983 | f.10.1 | V | Viral glycoprotein, central and dimerization domains | Plus-ssRNA |
| 101257 | a.190.1 | V | Flavivirus capsid protein C | Plus-ssRNA |
| 103145 | d.255.1 | V | Tombusvirus P19 core protein, VP19 | Plus-ssRNA |
| 89043 | a.178.1 | V | Soluble domain of poliovirus core protein 3a | Plus-ssRNA |
| 110304 | b.148.1 | V | Coronavirus RNA binding domain | Plus-ssRNA |
| 101816 | b.140.1 | V | Replicase NSP9 | Plus-ssRNA |
| 140367 | a.8.9 | V | Coronavirus NSP7–like | Plus-ssRNA |
| 143076 | d.302.1 | V | Coronavirus NSP8–like | Plus-ssRNA |
| 144246 | g.86.1 | V | Coronavirus NSP10–like | Plus-ssRNA |
| 103068 | d.254.1 | V | Nucleocapsid protein dimerization domain | Plus-ssRNA |
| 117066 | b.1.24 | V | Accessory protein X4 (ORF8, ORF7a) | Plus-ssRNA |
| 143587 | d.318.1 | V | SARS receptor binding domain–like | Plus-ssRNA |
| 159936 | d.15.14 | V | NSP3A-like | Plus-ssRNA |
| 160099 | d.346.1 | V | SARS Nsp1–like | Plus-ssRNA |
| 140506 | a.30.8 | V | FHV B2 protein–like | Plus-ssRNA |
| 144251 | g.87.1 | V | Viral leader polypeptide zinc finger | Plus-ssRNA |
| 141666 | b.164.1 | V | SARS ORF9b–like | Plus-ssRNA |
| 55671 | d.102.1 | V | Regulatory factor Nef | ssRNA-RT |
| 56502 | d.172.1 | V | gp120 core | ssRNA-RT |
| 57647 | g.34.1 | V | HIV-1 VPU cytoplasmic domain | ssRNA-RT |
| 49749 | b.121.2 | EV | Group II dsDNA viruses VP | dsDNA |
| 103417 | e.48.1 | EV | Major capsid protein VP5 | dsDNA |
| 140713 | a.251.1 | EV | Phage replication organizer domain | dsDNA |
| 161008 | e.76.1 | EV | Viral glycoprotein ectodomain–like | dsDNA, minus-ssRNA |
| 110132 | b.147.1 | EV | BTV NS2-like ssRNA binding domain | dsRNA |
| 82856 | e.42.1 | EV | L-A virus major coat protein | dsRNA |
| 140809 | a.260.1 | EV | Rhabdovirus nucleoprotein–like | Minus-ssRNA |
| 101399 | a.206.1 | EV | P40 nucleoprotein | Minus-ssRNA |
| 55405 | d.85.1 | EV | RNA bacteriophage capsid protein | Minus-ssRNA |
| 68918 | a.140.4 | BV | Recombination endonuclease VII, C-terminal and dimerization domains | dsDNA |
| 50017 | b.32.1 | BV | gp9 | dsDNA |
| 58046 | h.1.17 | BV | Fibritin | dsDNA |
| 56826 | e.27.1 | BV | Upper collar protein gp10 (connector protein) | dsDNA |
| 161234 | g.91.1 | BV | E7 C-terminal domain–like | dsDNA |
| 140919 | a.263.1 | BV | DNA terminal protein | dsDNA |
| 89064 | a.179.1 | BV | Replisome organizer (g39p helicase loader/inhibitor protein) | dsDNA |
| 160570 | d.368.1 | BV | YonK-like | dsDNA |
| 51327 | b.90.1 | BV | Head binding domain of phage P22 tailspike protein | dsDNA |
| 141658 | b.163.1 | BV | Bacteriophage trimeric proteins domain | dsDNA |
| 64210 | d.186.1 | BV | Head-to-tail joining protein W, gpW | dsDNA |
| 51274 | b.85.2 | BV | Head decoration protein D (gpD, major capsid protein D) | dsDNA |
| 159865 | d.186.2 | BV | XkdW-like | dsDNA |
| 101059 | a.159.3 | BV | B-form DNA mimic Ocr | dsDNA |
| 58091 | h.4.2 | BV | Clostridium neurotoxins, “coiled-coil” domain | dsDNA |
| 47681 | a.49.1 | BV | C-terminal domain of B transposition protein | dsDNA |
| 58059 | h.2.1 | BV | Tetramerization domain of the Mnt repressor | dsDNA |
| 54328 | d.15.5 | BV | Staphylokinase/streptokinase | dsDNA |
| 64465 | d.196.1 | BV | Outer capsid protein sigma 3 | dsRNA |
| 57987 | h.1.4 | BV | Inovirus (filamentous phage) major coat protein | ssDNA |
| 160940 | e.66.1 | BEV | Api92-like | dsDNA |
| 160459 | d.362.1 | BEV | BLRF2-like | dsDNA |
| 109859 | a.214.1 | BEV | NblA-like | dsDNA |
| 54334 | d.15.6 | BEV | Superantigen toxins, C-terminal domain | dsDNA |
| 51225 | b.83.1 | BEV | Fiber shaft of virus attachment proteins | dsDNA, dsRNA |
| 49835 | b.21.1 | BEV | Virus attachment protein globular domain | dsDNA, dsRNA |
| 50203 | b.40.2 | BEV | Bacterial enterotoxins | dsDNA, ssDNA |
| 111474 | h.3.3 | BEV | Coronavirus S2 glycoprotein | dsDNA, plus-ssRNA |
| 56831 | e.28.1 | BEV | Reovirus inner layer core protein p3 | dsRNA |
| 109801 | a.30.5 | AV | Hypothetical protein D-63 | dsDNA |
| 161229 | g.90.1 | ABV | E6 C-terminal domain–like | dsDNA |
| 74748 | a.154.1 | ABV | Variable surface antigen VlsE | dsDNA |
| 143602 | d.321.1 | ABEV | STIV B116-like | dsDNA |
| 58064 | h.3.1 | ABEV | Influenza hemagglutinin (stalk) | dsDNA, minus-ssRNA |