Table 5 Fine-mapping of the DLEU1 locus.

MAF (controls in %) and r2 (with rs2812197) are calculated from a joint set of DE1 and DE2, ORs and P values from the pooled analysis of DE1 and DE2. Second and third P value columns are from conditional analysis.

VariantMAFOR (CI)PP (rs2812197)P (rs9591325)r2Reference
rs281219738.40.86 (0.82–0.91)9.95 × 10−94.79 × 10−51.00
rs80632148.50.89 (0.85–0.94)6.36 × 10−60.812.02 × 10−30.66(5)
rs80634946.01.10 (1.04–1.15)2.73 × 10−40.990.0190.41(4, 21)
rs95913258.10.78 (0.70–0.85)2.26 × 10−79.13 × 10−40.14
rs95962708.10.78 (0.71–0.86)4.45 × 10−71.49 × 10−30.270.14 (0.99*)(6)

*r2 with rs9591325.