MAF (controls in %) and r2 (with rs2812197) are calculated from a joint set of DE1 and DE2, ORs and P values from the pooled analysis of DE1 and DE2. Second and third P value columns are from conditional analysis.
Variant | MAF | OR (CI) | P | P (rs2812197) | P (rs9591325) | r2 | Reference |
rs2812197 | 38.4 | 0.86 (0.82–0.91) | 9.95 × 10−9 | 4.79 × 10−5 | 1.00 | ||
rs806321 | 48.5 | 0.89 (0.85–0.94) | 6.36 × 10−6 | 0.81 | 2.02 × 10−3 | 0.66 | (5) |
rs806349 | 46.0 | 1.10 (1.04–1.15) | 2.73 × 10−4 | 0.99 | 0.019 | 0.41 | (4, 21) |
rs9591325 | 8.1 | 0.78 (0.70–0.85) | 2.26 × 10−7 | 9.13 × 10−4 | 0.14 | ||
rs9596270 | 8.1 | 0.78 (0.71–0.86) | 4.45 × 10−7 | 1.49 × 10−3 | 0.27 | 0.14 (0.99*) | (6) |
*r2 with rs9591325.