Table 1 Comparison of the sensitivity of the CTC cluster assay and conventional CTC expansion techniques. N.D., not determined.
Cancer
type
Samples
validated
DurationCulture typePre-
enrichment
Efficiency in cultureCorrelation to
treatment
Reference
Breast36>6 monthsCell lines, long-termYes16.70%N.D.(8)
Breast8<1 month or
≧1 month
Colonies (short-term) or
cell lines (long-term)
Yes37.50%N.D.(7)
Colon71>2 monthsCell lines, long-termYes2.80%N.D.(52)
Prostate17>6 monthsOrganoid lines, long-termYes~15–20%N.D.(9)
Breast732 weeksPrimary CTC cluster (short-
term)
No19.6–59.3% (depending on
treatment time point)
YesThis work