Table 2 Association of teprenone with depressive events in patient using peginterferon α-2a, peginterferon α-2b, or ribavirin. CI, confidence interval.
Cases with
depression, n
Non-
cases, n
Reporting odds
ratio (95% CI)
Total (male and female)
  Teprenone not present162641,3481.82 (1.73–1.92)
  Teprenone present104031.13 (0.61–2.12)
Male
  Teprenone not present90423,3932.23 (2.08–2.39)
  Teprenone present51961.42 (0.59–3.46)
Female
  Teprenone not present72217,9551.67 (1.55–1.80)
  Teprenone present52070.99 (0.41–2.42)