Table 2 Changes in the microscopic rate constants in Aβ42 aggregation in the presence of the different DesAbs used in this work (elongation, k+; primary nucleation, kn; and secondary nucleation, k2).
Antibodyk+knk+k2k+knk2
DesAb3–91.2205.168.7173.858.2
DesAb13–198.01210.9760.9150.194.8
DesAb18–253.9723.43.2183.60.8
DesAb29–361.535.1206.223.4137.4
DesAb36–429.97.41270.812.9