Table 1 Optimization of reaction conditions for the construction of 3,5-diaryl pyridines.

Reaction conditions: 1a (0.1 mmol, 1 equiv.), catalyst (0.01 mmol, 0.1 equiv.), ligand (0.01 mmol, 0.1 equiv.), and additive (0.02 mmol, 0.2 equiv.) in solvent (1.0 ml) at T (°C) for 48 hours. MS, molecular sieves; phen, 1,10-phenanthroline; bpy, bipyridine; THF, tetrahydrofuran; n.r., no reaction.


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