Table 1 Independent and combined biasing effects of the sex chromosomes and gonadal hormones in BCa.

The HR is determined using the Cox proportional hazard model. Chro, sex chromosomes; n, mouse numbers; O, ovary; T, testis.

nHRP95% CI
Chro (XY vs. XX)(52, 44)2.5490.00021.55–4.28
Gonad (T vs. O)(49, 47)4.714<0.00012.77–8.28
Combination(29, 24)12.39<0.00015.54–31.63