Table 1 Class 1 genes with functional group, human and budding yeast orthologs, MC (%) at the indicated time points, average cell length 24 hours after −N, cell number increment 24 hours after −N, and major DNA peaks in VE and 24 hours after −N, measured by FACS.
Functional groupStrain nameOrthologMC (%)Cell
length
Cell
number
Major DNA
peak
HumanBudding
yeast
VE24
hours
1
week
2
weeks
3
weeks
4
weeks
−N 24
hours
(μm)
Fold
change
VE-N 24
hours
WT104.497.887.8103.390.690.04.93.62C1C
Protein
phosphatase–
related
Nem1-
Spo7
Δnem1CTDNEP1NEM196.780.05.03.32.02.85.43.02C1C
ΔSPBC902.03CNEP1R1SPO7108.380.04.80.00.00.06.22.42C1C/2C
CWIΔrnc1HNRNPKPBP2103.3100.096.77.03.30.85.03.82C1C
PP1Δctf1CSTF2TRNA1566.778.320.00.00.00.04.84.02C1C
PP2AΔmug134ENSAIGO1110.0106.750.08.35.05.010.52.42C2C
Δpar1PPP2R5BRTS193.388.348.30.00.00.05.02.22C2C
Δypa1PPP2R4RRD186.775.070.05.84.34.75.82.22C2C
Protein kinaseΔkin1MARKKIN1101.765.023.70.00.00.05.82.52C2C
RNA/protein
process
Δexo2XRN1XRN141.761.78.80.00.00.010.11.72C2C
Δrpl2002RPL18ARPL20B105.0106.746.71.25.80.04.43.52C1C
Δsbh1SEC61BSBH161.763.35.01.70.01.24.64.12C1C
Vesicle
transport
Δvps3TGFBRAP1VPS3115.045.01.00.00.00.05.12.42C1C
Δvps26VPS26BPEP8113.363.325.01.73.31.76.61.62C2C
Δvps35VPS35VPS3578.330.05.00.70.70.37.21.92C2C
TransporterΔvht1SLC17VHT170.090.010.00.00.00.06.21.81C1C
VacuoleΔaut12MON1BMON1100.071.70.00.00.00.08.21.42C1C/2C
Δvac7VAC7108.371.70.00.00.00.08.52.12C2C
ΔSPBC83.16cTTC39BYKR018C103.390.07.50.00.00.04.93.62C1C
Metabolism
(antioxidant)
Δsod2SOD2SOD276.748.33.70.00.00.05.12.02C1C
Δspe1ODCC1SPE190.083.375.04.21.01.85.03.11C/2C1C/2C