Table 2 Scope for the N-PtBu–directed C7-(hetero)arylation of indoles.

Reaction conditions: 1a (0.20 mmol), 2 (0.40 mmol), Rh(PPh3)3Cl (6.0 mol%), LiOtBu (3.0 equiv) in m-xylene (1.0 ml) at 150°C, 24 hours, under Ar, isolated yields.


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*80°C.

†100°C.

‡130°C.

§Using 1t (0.10 mmol), 2 (0.40 mmol), Rh(PPh3)3Cl (12.0 mol%), and LiOtBu (6.0 equiv) in m-xylene (1.0 ml) at 100°C.