Table 1 Summary of metastasis formation in TNBC orthotopic and lung metastasis models.

Metastatic sitePBS (sham)Free DoxIgG-Dox-LPICAM-Dox-LPEGFR-Dox-LPDCL-Dox_4.2/1
Orthotopic breast tumor model
Brain0/80/80/70/90/80/10
Lung1/80/80/70/91/80/10
Heart0/80/80/70/90/80/10
Liver3/80/82/70/91/80/10
Spleen3/80/82/71/91/81/10
Kidney0/80/80/70/90/80/10
Right hind limb (tumor bearing)6/88/85/74/95/81/10
Left hind (normal)1/80/80/72/91/80/10
Total7/88/86/75/95/81/10
Lung metastasis model
Brain0/80/80/80/80/80/8
Lung8/85/86/82/86/80/8
Heart0/80/80/80/80/80/8
Liver2/80/81/80/80/80/8
Spleen1/80/80/80/80/80/8
Kidney0/80/80/80/80/80/8
Hind limbs (normal)0/80/80/80/80/80/8
Total8/85/86/82/86/80/8