Table 2 Platelet reactivity of PWH versus seronegative controls.

Maximum platelet aggregation in response to various agonists tested using platelet aggregometry and summarized as median (IQR).

Seronegative
controls
(n = 14)
PWH (n = 15)P
Spontaneous
aggregation
2.0 (2.3)3.0 (1.0)0.008
ADP
  0.4 μM5.0 (10.8)5.0 (5.0)0.946
  1.0 μM18.0 (24.5)14.5 (9.8)0.701
  20 μM85.5 (13.3)84.0 (19.8)0.701
Arachidonic acid
  150 μM1.0 (2.5)3.0 (4.5)0.133
  500 μM73.0 (22.0)86.5 (14.8)0.013
Collagen
  0.05 μg/ml2.0 (2.0)3.0 (5.0)0.019
  2.0 μg/ml82.5 (15.3)78.0 (17.0)0.571
Epinephrine
  0.0 5 μM5.5 (17.5)5.5 (5.3)0.635
  0.1 μM7.0 (49.8)6.5 (6.5)0.701
  5.0 μM82.5 (22.0)88.0 (39.0)0.488