Table 2 Substrate scope, late-stage modification, and deuterated drug synthesis.

Reaction conditions: substrates a (1.0 equiv), DMTT (1 to 2 equiv), and K2CO3 (2 to 4 equiv) in 2 ml of MeCN for 12 hours. Isolated yields were presented.


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*Reaction conditions: substrates a (1.0 equiv), DMTT (1.0 equiv), and KOH (2.0 equiv) in 2 ml of MeCN/H2O (v:v = 1/1) for 12 hours. Isolated yields were presented.