Table 1 Comparison of different atom-mapping tools.

Comparing RXNMapper to Indigo (17) and Mappet (16).

RXNMapperIndigo (17)Mappet (16)
Average time
(short)
6.4 ms17.0 msSlower than
Indigo
Average time
(strongly
unbalanced)
7.7 ms2400 msNot handled
Quality on
complex
reactions
HighLowHigh
Quality on
strongly
unbalanced
reactions
HighLow
Open-source
code?
YesYesNo